Sudden Presence Of Carbon Dioxide In The Subcutis
- stimulates the encephalobular vasomotor center and vasomotor centres of the spinal cord, which results in the contraction of the abdominal bed, washing out of the depot blood and blood pressure increase.
- stimulates the centres mentioned above in a reflexive way through chemoreceptors, when the blood pressure increase stimulates baroreceptors.
- widens coronary vessels, improves blood circulation in the myocardium, increases its tonus and its minute volume.
- stimulates vagus that further causes bradycardia and decrease of blood pressure.
- hypercapnia stimulates acidosis and changes the haemoglobin dissociation curve
- it is a strong peripheral vasodilator
Contraindication of INDAP INSUF
- Inflammation of the skin, hypodermis and veins at the injection site
- Varicose syndrome, haemorrhagic conditions and fear of the patient
- Occurrence of pigmented nevi at the injection site
- Defects of skin and subcutaneous tissues at application site
- INDAP INSUF User’s Guide Page | 26
- Cardiac, pulmonary or renal failure
- Feverishness, acute infectious diseases
- Pregnancy
- Hyperthyroidism
Side effects
- Short-term burning sensation, pressure, pain, itching, local neurovegetative reactions, etc. at the injection site.
- Local changes at the injection site – erythema, capillary haemorrhage, minor hematoma, allergic dermatitis at the injection site, abscess exceptionally.
- Increased caution in the case of vegetatively unstable individuals (induction of tachycardia, collapse states)
- Ensure sufficient time interval in the event of simultaneous physical therapy (thermotherapy, cryotherapy, hydrotherapy, mechanotherapy, electrotherapy).
- Increased caution in the case of long-term medication (anticoagulants, antiplatelet agents, analgesics, vasodilators, corticosteroids, nicotine substitution)
